This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Fuste, M. C.
Right arrow Articles by Loren, J. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fuste, M. C.
Right arrow Articles by Loren, J. G.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, Nov 1996, 2760-2765, Vol 34, No. 11
Copyright © 1996 by the American Society for Microbiology. All rights reserved.

Clonality of multidrug-resistant nontypeable strains of Haemophilus influenzae

MC Fuste, MA Pineda, J Palomar, M Vinas and JG Loren
Departament de Microbiologia i Parasitologia Sanitaries, Facultat de Farmacia, Universitat de Barcelona, Spain.

The genetic structure of a population of multidrug-resistant nontypeable (unencapsulated) Haemophilus influenzae strains isolated at a hospital in Barcelona, Spain, was investigated by using multilocus enzyme electrophoresis to determine the allelic variation in 15 structural loci. In our study we have also included some antimicrobial agent-susceptible strains isolated at the same hospital. All enzymes were polymorphic for two to eight electromorphs, and the analysis revealed 43 distinct electrophoretic types among the 44 isolates. The mean genetic diversity of the entire population was 0.55. Multilocus linkage disequilibrium analysis of the isolates revealed a strong association between alleles, suggesting little possibility of recombination. Furthermore, the dendrogram and the allele mismatch distribution are typical of a population with no extensive genetic mixing.


This article has been cited by other articles:

  • Karpanoja, P., Nyberg, S. T., Bergman, M., Voipio, T., Paakkari, P., Huovinen, P., Sarkkinen, H., and the Finnish Study Group for Antimicrobial Resi, (2008). Connection between Trimethoprim-Sulfamethoxazole Use and Resistance in Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Antimicrob. Agents Chemother. 52: 2480-2485 [Abstract] [Full Text]  
  • Augustynowicz, E., Gzyl, A., Szenborn, L., Banys, D., Gniadek, G., Slusarczyk, J. (2003). Comparison of usefulness of randomly amplified polymorphic DNA and amplified-fragment length polymorphism techniques in epidemiological studies on nasopharyngeal carriage of non-typable Haemophilus influenzae. J Med Microbiol 52: 1005-1014 [Abstract] [Full Text]  
  • Farfan, M., Minana-Galbis, D., Fuste, M. C., Loren, J. G. (2002). Allelic Diversity and Population Structure in Vibrio cholerae O139 Bengal Based on Nucleotide Sequence Analysis. J. Bacteriol. 184: 1304-1313 [Abstract] [Full Text]  
  • Rius, N., Fusté, M. C., Guasp, C., Lalucat, J., Lorén, J. G. (2001). Clonal Population Structure of Pseudomonas stutzeri, a Species with Exceptional Genetic Diversity. J. Bacteriol. 183: 736-744 [Abstract] [Full Text]  
  • Han, S.-R., Zschausch, H.-C. E., Meyer, H.-G. W., Schneider, T., Loos, M., Bhakdi, S., Maeurer, M. J. (2000). Helicobacter pylori: Clonal Population Structure and Restricted Transmission within Families Revealed by Molecular Typing. J. Clin. Microbiol. 38: 3646-3651 [Abstract] [Full Text]  
  • Farfán, M., Miñana, D., Fusté, M. C., Lorén, J. G. (2000). Genetic relationships between clinical and environmental Vibrio cholerae isolates based on multilocus enzyme electrophoresis. Microbiology 146: 2613-2626 [Abstract] [Full Text]  
  • Gomez-De-Leon, P., Santos, J. I., Caballero, J., Gomez, D., Espinosa, L. E., Moreno, I., Piñero, D., Cravioto, A. (2000). Genomic Variability of Haemophilus influenzae Isolated from Mexican Children Determined by Using Enterobacterial Repetitive Intergenic Consensus Sequences and PCR. J. Clin. Microbiol. 38: 2504-2511 [Abstract] [Full Text]  
  • Gazagne, L., Delmas, C., Bingen, E., Dabernat, H. (1998). Molecular Epidemiology of Ampicillin-Resistant Non-beta -Lactamase-Producing Haemophilus influenzae. J. Clin. Microbiol. 36: 3629-3635 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»