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Journal of Clinical Microbiology, Feb 1997, 508-510, Vol 35, No. 2
Copyright © 1997 by the American Society for Microbiology. All rights reserved.

Study of an outbreak of cefoxitin-resistant Klebsiella pneumoniae in a general hospital

M Gazouli, ME Kaufmann, E Tzelepi, H Dimopoulou, O Paniara and LS Tzouvelekis
Department of Bacteriology, Hellenic Pasteur Institute, Athens, Greece.

During a 3-month period, six Klebsiella pneumoniae isolates resistant to cefoxitin and penicillin-inhibitor combinations were derived from patients in the intensive care unit of a hospital in Athens, Greece. Enterobacterial repetitive intergenic consensus PCR and pulsed-field gel electrophoresis provided evidence of the clonal origin of the isolates. Conventional techniques and ribotyping were inadequate in proving that the isolates were related. Resistance was due to a plasmidic class C beta-lactamase.


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