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Journal of Clinical Microbiology, 07 1997, 1870-1872, Vol 35, No. 7
Copyright © 1997 by the American Society for Microbiology. All rights reserved.

Determination of genotypes of hepatitis C virus in Venezuela by restriction fragment length polymorphism

FH Pujol, CL Loureiro, M Devesa, L Blitz, K Parra, S Beker and F Liprandi
Laboratorio Biologia de Virus, CMBC, IVIC, Caracas, Venezuela. fpujol@pasteur.ivic.ve

Hepatitis C virus genotypes in Venezuela were analyzed by restriction fragment length polymorphism in the 5' noncoding region. The absence of BstUI digestion was found to be a useful marker for genotype 2 specimens. From 122 serum samples, 66, 20, and 2.5% were classified as genotypes 1, 2, and 3, respectively; 0.8% were classified as genotype 4; and 10% appeared to be mixed infections.


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