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Journal of Clinical Microbiology, Jul 1997, 1873-1875, Vol 35, No. 7
Copyright © 1997 by the American Society for Microbiology. All rights reserved.

Increased prevalence of genotype F hepatitis B virus isolates in Buenos Aires, Argentina

PF Telenta, GP Poggio, JL Lopez, J Gonzalez, A Lemberg and RH Campos
Catedra de Virologia, Facultad de Farmacia y Bioquimica, Universidadde Buenos Aires, Capital Federal, Argentina.

The genomic coding region of the hepatitis B surface antigen (HBsAg) was partially sequenced from 12 HBsAg-positive sera of carriers residing in Buenos Aires, Argentina. A phylogenetic analysis groups the 12 isolates into genotypes A (n = 4), B (n = 1), D (n = 2), and F (n = 5). The occurrence of genotypes A and D is not unexpected, considering the mainly European origin of the studied population. The high prevalence of genotype F and its genetic composition support the suggestion that F strains originated in native populations of the New World.


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