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Journal of Clinical Microbiology, January 1998, p. 296-298, Vol. 36, No. 1
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Improving the Yield of Blood Cultures for Patients with Early Lyme Disease

Gary P. Wormser,1,* John Nowakowski,1 Robert B. Nadelman,1 Susan Bittker,1 Denise Cooper,1 and Charles Pavia1,2

Division of Infectious Diseases, Department of Medicine, New York Medical College, Valhalla, New York 10595,1 and New York College of Osteopathic Medicine Immunodiagnostic Laboratory, Old Westbury, New York 115682

Received 2 June 1997/Returned for modification 17 July 1997/Accepted 10 October 1997

This study was designed to improve the recovery of Borrelia burgdorferi from blood. With the techniques used, B. burgdorferi could be recovered from the blood of approximately 25% of patients with early Lyme disease associated with erythema migrans. Serum was a better source of culture material than whole blood. The volume of blood cultured correlated directly with yield, particularly for patients with a single erythema migrans lesion.

* Corresponding author. Mailing address: Division of Infectious Diseases, Room 209SE, Macy Pavilion, Westchester County Medical Center, Valhalla, NY 10595. Phone: (914) 493-8865. Fax: (914) 493-7289.

Journal of Clinical Microbiology, January 1998, p. 296-298, Vol. 36, No. 1
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


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