This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Katayama, Y.
Right arrow Articles by Hotta, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Katayama, Y.
Right arrow Articles by Hotta, H.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, January 1998, p. 299-301, Vol. 36, No. 1
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Detection of Measles Virus mRNA from Autopsied Human Tissues

Yuko Katayama,1 Kiyoyasu Kohso,1 Akiyoshi Nishimura,2 Yoshitsugu Tatsuno,3 Morio Homma,4 and Hak Hotta1,*

Department of Microbiology,1 and Department of Legal Medicine,3 Kobe University School of Medicine, Chuo-ku, Kobe, Hyogo 650, Department of Legal Medicine, Shiga University of Medical Science, Ohtsu, Shiga 520-21,2 and Faculty of Home Economics, Kobe Women's University, Suma-ku, Kobe, Hyogo 654,4 Japan

Received 25 August 1997/Returned for modification 7 October 1997/Accepted 28 October 1997

By reverse transcription-PCR, measles virus (MV) mRNA was detected in the brain, kidney, spleen, liver, and lung tissues obtained from 23 (45.1%) of 51 autopsy subjects, with the detection rates of each tissue ranging from 8 to 20%. Sequence analysis revealed frequent mutations in the corresponding viral protein. These results suggest that MV mutants commonly persist in apparently healthy individuals.

* Corresponding author. Mailing address: Department of Microbiology, Kobe University School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Hyogo 650, Japan. Phone: 81-78-341-7451, ext. 3300. Fax: 81-78-351-6347. E-mail: hotta{at}kobe-u.ac.jp.

Journal of Clinical Microbiology, January 1998, p. 299-301, Vol. 36, No. 1
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Garg, R K (2002). Subacute sclerosing panencephalitis. Postgrad. Med. J. 78: 63-70 [Abstract] [Full Text]  
  • Halsey, N. A., Hyman, S. L., the Conference Writing Panel, (2001). Measles-Mumps-Rubella Vaccine and Autistic Spectrum Disorder: Report From the New Challenges in Childhood Immunizations Conference Convened in Oak Brook, Illinois, June 12-13, 2000. Pediatrics 107: 84e-84 [Abstract] [Full Text]  
  • Grayeli, A. B., Palmer, P., Tran Ba Huy, P., Soudant, J., Sterkers, O., Lebon, P., Ferrary, E. (2000). No Evidence of Measles Virus in Stapes Samples from Patients with Otosclerosis. J. Clin. Microbiol. 38: 2655-2660 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»