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Journal of Clinical Microbiology, January 1998, p. 315-316, Vol. 36, No. 1
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Low Sensitivity of Peripheral Blood Smear for Diagnosis of Subclinical Visceral Leishmaniasis in Human Immunodeficiency Virus Type 1-Infected Patients

J. Delgado,* J. A. Pineda, J. Macías, C. Regordán, J. A. Gallardo, M. Leal, A. Sanchez-Quijano, and E. Lissen

Viral Hepatitis & AIDS Study Group, Virgen del Rocío University Hospital, Seville, Spain

Received 23 June 1997/Returned for modification 8 September 1997/Accepted 8 October 1997

The peripheral blood smear is an easy method for the diagnosis of symptomatic visceral leishmaniasis (VL) in human immunodeficiency virus type 1 (HIV-1)-infected patients. However, its efficiency in diagnosing subclinical VL remains unknown. In this study, Leishmania amastigotes were seen in blood smears from 1 of 13 HIV-1-positive individuals with subclinical VL. This shows that this procedure is not suitable for subclinical-VL diagnosis.

* Corresponding author. Mailing address: Department of Internal Medicine, Viral Hepatitis & AIDS Study Group, Virgen del Rocío University Hospital, Avda. Manuel Siurot s/n, 41013 Seville, Spain. Phone: 34-5-4248154. Fax: 34-5-4248249. E-mail: iaguado{at}cica.es.

Journal of Clinical Microbiology, January 1998, p. 315-316, Vol. 36, No. 1
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


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