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Journal of Clinical Microbiology, December 1998, p. 3505-3508, Vol. 36, No. 12
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Tick-Borne Relapsing Fever in British Columbia, Canada: First Isolation of Borrelia hermsii

Satyendra N. Banerjee,1 Maya Banerjee,1 Keerthi Fernando,1 Willy Burgdorfer,2 and Tom G. Schwan2,*

B.C. Centre for Disease Control Society, Vector-Borne Diseases Laboratory, Vancouver, British Columbia V5Z 4R4, Canada,1 and Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 598402

Received 8 July 1998/Returned for modification 18 August 1998/Accepted 3 September 1998

The spirochete that causes tick-borne relapsing fever, Borrelia hermsii, was isolated in pure culture during 1995 and 1996 from three acutely ill human patients infected in southern British Columbia, Canada. The geographic area of exposure is a known focus of this disease dating back to 1930 when the first case was recognized in a human. Analyses of plasmid DNA, protein profiles, and reactivity with a species-specific monoclonal antibody identified the new isolates of spirochetes as B. hermsii, all of which were most similar to an isolate of this spirochete from northern California described previously. These are the first reported isolates of B. hermsii from Canada.


* Corresponding author. Mailing address: Rocky Mountain Laboratories, 903 South 4th St., Hamilton, MT 59840. Phone: (406) 363-9250. Fax: 406 363-9371. E-mail: tom_schwan{at}nih.gov.


Journal of Clinical Microbiology, December 1998, p. 3505-3508, Vol. 36, No. 12
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.



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