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Journal of Clinical Microbiology, December 1998, p. 3691-3693, Vol. 36, No. 12
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Prevalence of Astrovirus Infection among Chilean Children with Acute Gastroenteritis

Aldo Gaggero,1,* Miguel O'Ryan,2 Jacqueline S. Noel,3 Roger I. Glass,3 Stephan S. Monroe,3 Nora Mamani,2 Valeria Prado,2 and Luis F. Avendaño1

Programa de Virología1 and Programa de Microbiología,2 Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile, and Viral Gastroenteritis Section, Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 303333

Received 23 April 1998/Returned for modification 26 June 1998/Accepted 28 August 1998

The frequency of astrovirus infection in 456 Chilean children with diarrhea was determined by enzyme-linked immunosorbent assay, reverse transcriptase PCR, and cell culture. Astrovirus was detected in 16.5% of rotavirus-negative and 7% of rotavirus-positive samples obtained from emergency rooms or hospitals and in 11% of samples from day care centers. HAst-1 was the predominant serotype identified.

* Corresponding author. Mailing address: Programa de Virología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Independencia 1027, Santiago, Chile. Phone: (56-2) 6786317. Fax: (56-2) 6786124. E-mail: agaggero{at}bitmed.med.uchile.cl.

Journal of Clinical Microbiology, December 1998, p. 3691-3693, Vol. 36, No. 12
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


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