This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Schultz-Cherry, S.
Right arrow Articles by Hinshaw, V. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Schultz-Cherry, S.
Right arrow Articles by Hinshaw, V. S.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, December 1998, p. 3718-3720, Vol. 36, No. 12
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Mink Lung Epithelial Cells: Unique Cell Line That Supports Influenza A and B Virus Replication

Stacey Schultz-Cherry,1,* Naomi Dybdahl-Sissoko,2 Martha McGregor,2 and Virginia S. Hinshaw2

Southeast Poultry Research Laboratory, Agricultural Research Service, U.S. Department of Agriculture, Athens, Georgia 30605,1 and Department of Pathobiological Sciences, University of Wisconsin---Madison, Madison, Wisconsin 537062

Received 2 June 1998/Returned for modification 13 August 1998/Accepted 23 September 1998

We have demonstrated for the first time that a mink lung epithelial cell line (Mv1Lu) supports the replication of influenza A and B viruses, including the recently isolated H5N1 avian and human Hong Kong strains, to titers comparable to those in MDCK cells. These results suggest that Mv1Lu cells might serve as an alternative system for the isolation and cultivation of influenza A and B viruses and may be useful for vaccine development.

* Corresponding author. Mailing address: Southeast Poultry Research Laboratory, USDA-ARS, 934 College Station Rd., Athens, GA 30605. Phone: (706) 546-3464. Fax: (706) 546-3161. E-mail: sschultzcherry{at}sprynet.com.

Journal of Clinical Microbiology, December 1998, p. 3718-3720, Vol. 36, No. 12
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Sanchez-Cordon, P. J., Nunez, A., Salguero, F. J., Pedrera, M., Fernandez de Marco, M., Gomez-Villamandos, J. C. (2005). Lymphocyte Apoptosis and Thrombocytopenia in Spleen during Classical Swine Fever: Role of Macrophages and Cytokines. Vet Pathol 42: 477-488 [Abstract] [Full Text]  
  • Fong, C. K. Y., Lee, M. K., Griffith, B. P. (2000). Evaluation of R-Mix FreshCells in Shell Vials for Detection of Respiratory Viruses. J. Clin. Microbiol. 38: 4660-4662 [Abstract] [Full Text]  
  • Root, C. N., Wills, E. G., McNair, L. L., Whittaker, G. R. (2000). Entry of influenza viruses into cells is inhibited by a highly specific protein kinase C inhibitor. J. Gen. Virol. 81: 2697-2705 [Abstract] [Full Text]  
  • Huang, Y. T., Turchek, B. M. (2000). Mink Lung Cells and Mixed Mink Lung and A549 Cells for Rapid Detection of Influenza Virus and Other Respiratory Viruses. J. Clin. Microbiol. 38: 422-423 [Abstract] [Full Text]  
  • Navarro-Marí, J. M., Sanbonmatsu-Gámez, S., Pérez-Ruiz, M., De La Rosa-Fraile, M. (1999). Rapid Detection of Respiratory Viruses by Shell Vial Assay Using Simultaneous Culture of HEp-2, LLC-MK2, and MDCK Cells in a Single Vial. J. Clin. Microbiol. 37: 2346-2347 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»