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Journal of Clinical Microbiology, February 1998, p. 563-565, Vol. 36, No. 2
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

Genetic Heterogeneity of Strains of Neisseria meningitidis Belonging to Serotype 22 Isolated in the Czech Republic

Martin Musilek,1 Dario Giorgini,2 Nora Hamadouche,2 Paula Kriz,1 and Muhamed-Kheir Taha2,*

National Reference Laboratory for Meningococcal Infections, NIPH, Prague, Czech Republic,1 and Unité des Neisseria, Institut Pasteur, 75724 Paris Cedex 15, France2

Received 1 August 1997/Returned for modification 26 September 1997/Accepted 3 November 1997

Strains of Neisseria meningitidis of serogroup B isolated in the Czech Republic frequently belong to serotype 22. We analyzed the genetic relationships among strains of this serotype by using the multilocus enzyme electrophoresis technique and the polymorphism of the pilA gene. Our results indicate that these strains correspond to a highly heterogeneous population rather than to the expansion of a single clone.

* Corresponding author. Mailing address: Unité des Neisseria, Institut Pasteur, 28 Rue du Dr. Roux, 75724 Paris Cedex 15, France. Phone: 33 1 45 68 84 38. Fax: 33 1 45 68 83 38. E-mail: mktaha{at}pasteur.fr.

Journal of Clinical Microbiology, February 1998, p. 563-565, Vol. 36, No. 2
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Taha, M.-K. (2000). Simultaneous Approach for Nonculture PCR-Based Identification and Serogroup Prediction of Neisseria meningitidis. J. Clin. Microbiol. 38: 855-857 [Abstract] [Full Text]  
  • Urwin, R., Fox, A. J., Musilek, M., Kriz, P., Maiden, M. C. J. (1998). Heterogeneity of the PorB Protein in Serotype 22 Neisseria meningitidis. J. Clin. Microbiol. 36: 3680-3682 [Abstract] [Full Text]  


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