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Journal of Clinical Microbiology, June 1998, p. 1784-1786, Vol. 36, No. 6
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.

High Human Herpesvirus 8 Seroprevalence in the Homosexual Population in Switzerland

Nicolas Regamey,1 Gieri Cathomas,2 Martine Schwager,1 Marion Wernli,1 Thomas Harr,1 and Peter Erb1,*

Institute for Medical Microbiology, University of Basel, Basel,1 and Department of Pathology, University Hospital of Zürich, Zürich,2 Switzerland

Received 17 December 1997/Returned for modification 24 February 1998/Accepted 24 March 1998

The seroprevalence of human herpesvirus 8 (HHV-8) in the Swiss population was investigated. By enzyme-linked immunosorbent assay, sera reactive to the recombinant HHV-8 antigen orf 65.2 were found in 24% of human immunodeficiency virus (HIV)-positive patients without and in 92% of HIV-positive patients with Kaposi's sarcoma. Surprisingly, 20% of homosexual HIV-negative men, versus only 7% of heterosexual HIV-negative individuals and 5% of blood donors, had antibodies to HHV-8.

* Corresponding author. Mailing address: Institute for Medical Microbiology, University of Basel, Petersplatz 10, CH-4003 Basel, Switzerland. Phone: (41) 61 267 32 75. Fax: (41) 61 267 32 98. E-mail: erb{at}ubaclu.unibas.ch.

Journal of Clinical Microbiology, June 1998, p. 1784-1786, Vol. 36, No. 6
0095-1137/98/$04.00+0
Copyright © 1998, American Society for Microbiology. All rights reserved.


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