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Journal of Clinical Microbiology, January 1999, p. 199-201, Vol. 37, No. 1
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Usefulness of Leifson Staining Method in Diagnosis of Helicobacter pylori Infection

Raffaele Piccolomini,1,* Giovanni Di Bonaventura,1 Matteo Neri,2 Arturo Di Girolamo,3 Giovanni Catamo,1 and Eligio Pizzigallo3

Department of Biomedical Sciences, Section of Clinical Microbiology,1 and Department of Medicine and Aging Sciences, Section of Gastroenterology2 and Section of Infectious Diseases,3 "G. D'Annunzio" University, Chieti, Italy

Received 30 March 1998/Returned for modification 26 May 1998/Accepted 24 September 1998

The Leifson staining method was used to diagnose Helicobacter pylori infection and was compared to histology, culture, and the rapid urease test (RUT). Histology gave the best sensitivity (98%), compared to Leifson staining (97%), culture (92%), and RUT (85%) (P < 0.005). Leifson staining is a sensitive, rapid, economical method for diagnosis of H. pylori infection in dyspeptic patients.

* Corresponding author. Mailing address: Dipartimento di Scienze Biomediche, Università "G. D'Annunzio," Via dei Vestini 31, Chieti, Italy, I-66100. Phone: (39) 871-3555283. Fax: (39) 871-3555282. E-mail: r.piccolomini{at}dsb.unich.it.

Journal of Clinical Microbiology, January 1999, p. 199-201, Vol. 37, No. 1
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.




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