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Journal of Clinical Microbiology, January 1999, p. 233-234, Vol. 37, No. 1
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Definition of False-Positive Reactions in Screening for Hepatitis C Virus Antibodies

Matthias Schröter,* Heinz-Hubert Feucht, Peter Schäfer, Bernhard Zöllner, Susanne Polywka, and Rainer Laufs

Institut für Medizinische Mikrobiologie und Immunologie, Universitäts-Krankenhaus Eppendorf, 20246 Hamburg, Germany

Received 21 January 1998/Returned for modification 6 May 1998/Accepted 13 October 1998

The rate of false-positive hepatitis C virus enzyme immunoassay results was determined to be at least 10% among 1,814 reactive serum samples based on (i) negative results in an independent confirmation assay, (ii) negative PCR results, and (iii) no patients developing clinical or biochemical signs of hepatitis during a 1-year follow-up.

* Corresponding author. Mailing address: Institut für Medizinische Mikrobiologie und Immunologie, Universitäts-Krankenhaus Eppendorf, Martinistr. 52, 20246 Hamburg, Germany. Phone: 49-40.47173159. Fax: 49-40.47174062. E-mail: mschroeter{at}uke.uni-hamburg.de.

Journal of Clinical Microbiology, January 1999, p. 233-234, Vol. 37, No. 1
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Polywka, S., Schröter, M., Feucht, H.-H., Zöllner, B., Laufs, R. (2001). Relevance of Reactivity in Commercially Available Hepatitis C Virus Antibody Assays. J. Clin. Microbiol. 39: 1665-1668 [Abstract] [Full Text]  


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