This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Heurtin-Le Corre, C.
Right arrow Articles by Avril, J.-L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Heurtin-Le Corre, C.
Right arrow Articles by Avril, J.-L.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, January 1999, p. 266-269, Vol. 37, No. 1
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Increasing Incidence and Comparison of Nalidixic Acid-Resistant Salmonella enterica subsp. enterica Serotype Typhimurium Isolates from Humans and Animals

Christine Heurtin-Le Corre, Pierre-Yves Donnio, Monique Perrin, Marie-France Travert, and Jean-Loup Avril*

UPRES 12-34 Microbiologie, Faculté de Médecine, Université de Rennes I, 35033 Rennes, France

Received 15 June 1998/Returned for modification 22 July 1998/Accepted 29 September 1998

We determined the resistance to quinolone of 309 Salmonella enterica subsp. enterica serotype Typhimurium strains isolated from humans and animals (cattle, pigs, or poultry) in 1995 or 1996. Nalidixic acid resistance increased from 8.5% in 1995 to 18.6% in 1996. The highest resistance levels correlated with a mutation at Ser-83 (or Asp-82). All strains remained ciprofloxacin susceptible. Human and animal isolates were compared by pulsed-field gel electrophoresis, and the banding patterns of the human isolates most closely matched those of the bovine isolates.

* Corresponding author. Mailing address: UPRES 12-34 Microbiologie, Faculté de Médecine, Université de Rennes I, 35033 Rennes, France. Phone: (33) (2)99-33-69-52. Fax: (33) (2)99-33-68-88. E-mail: Jean-Loup.Avril{at}univ-rennes1.fr.

Journal of Clinical Microbiology, January 1999, p. 266-269, Vol. 37, No. 1
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Preisler, A., Mraheil, M. A., Heisig, P. (2006). Role of novel gyrA mutations in the suppression of the fluoroquinolone resistance genotype of vaccine strain Salmonella Typhimurium vacT (gyrA D87G). J Antimicrob Chemother 57: 430-436 [Abstract] [Full Text]  
  • Ling, J. M., Chan, E. W., Lam, A. W., Cheng, A. F. (2003). Mutations in Topoisomerase Genes of Fluoroquinolone-Resistant Salmonellae in Hong Kong. Antimicrob. Agents Chemother. 47: 3567-3573 [Abstract] [Full Text]  
  • Aarestrup, F. M., Wiuff, C., Molbak, K., Threlfall, E. J. (2003). Is It Time To Change Fluoroquinolone Breakpoints for Salmonella spp.?. Antimicrob. Agents Chemother. 47: 827-829 [Full Text]  
  • Liebana, E., Garcia-Migura, L., Clouting, C., Clifton-Hadley, F. A., Lindsay, E., Threlfall, E. J., McDowell, S. W. J., Davies, R. H. (2002). Multiple Genetic Typing of Salmonella enterica Serotype Typhimurium Isolates of Different Phage Types (DT104, U302, DT204b, and DT49) from Animals and Humans in England, Wales, and Northern Ireland. J. Clin. Microbiol. 40: 4450-4456 [Abstract] [Full Text]  
  • Liebana, E., Clouting, C., Cassar, C. A., Randall, L. P., Walker, R. A., Threlfall, E. J., Clifton-Hadley, F. A., Ridley, A. M., Davies, R. H. (2002). Comparison of gyrA Mutations, Cyclohexane Resistance, and the Presence of Class I Integrons in Salmonella enterica from Farm Animals in England and Wales. J. Clin. Microbiol. 40: 1481-1486 [Abstract] [Full Text]  
  • Breuil, J., Brisabois, A., Casin, I., Armand-Lefevre, L., Fremy, S., Collatz, E. (2000). Antibiotic resistance in salmonellae isolated from humans and animals in France: comparative data from 1994 and 1997. J Antimicrob Chemother 46: 965-971 [Abstract] [Full Text]  
  • Giraud, E., Cloeckaert, A., Kerboeuf, D., Chaslus-Dancla, E. (2000). Evidence for Active Efflux as the Primary Mechanism of Resistance to Ciprofloxacin in Salmonella enterica Serovar Typhimurium. Antimicrob. Agents Chemother. 44: 1223-1228 [Abstract] [Full Text]  
  • Daly, M., Buckley, J., Power, E., O'Hare, C., Cormican, M., Cryan, B., Wall, P. G., Fanning, S. (2000). Molecular Characterization of Irish Salmonella enterica Serotype Typhimurium: Detection of Class I Integrons and Assessment of Genetic Relationships by DNA Amplification Fingerprinting. Appl. Environ. Microbiol. 66: 614-619 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»