This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zaoutis, T.
Right arrow Articles by Klein, J. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zaoutis, T.
Right arrow Articles by Klein, J. D.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, October 1999, p. 3380-3383, Vol. 37, No. 10
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Antibiotic Susceptibilities of Group C and Group G Streptococci Isolated from Patients with Invasive Infections: Evidence of Vancomycin Tolerance among Group G Serotypes

Theoklis Zaoutis,1,2 Barbara Schneider,3 Lynn Steele Moore,3 and Joel D. Klein1,2,*

Division of Pediatric Infectious Diseases, Alfred I. duPont Hospital for Children,1 and Infectious Diseases Laboratory, Christiana Care Health System,3 Wilmington, Delaware, and Jefferson Medical College, Philadelphia, Pennsylvania2

Received 8 February 1999/Returned for modification 2 May 1999/Accepted 10 July 1999

A retrospective review of medical records for 32 patients with invasive group C streptococcus (GCS) or group G streptococcus (GGS) infections was performed. MICs and minimum bactericidal concentrations (MBCs) of penicillin, erythromycin, and vancomycin for all isolates were obtained. Tolerance of vancomycin, defined as an MBC 32 or more times higher than the MIC, was exhibited by 18 GGS isolates (54%). The identification of tolerance in clinical isolates of GGS and GCS may have clinical implications in treating these seriously ill patients.

* Corresponding author. Mailing address: Division of Pediatric Infectious Diseases, Alfred I. duPont Hospital for Children, P.O. Box 269, Wilmington, DE 19899. Phone: (302) 651-4421. Fax: (302) 651-4463. E-mail: jklein{at}nemours.org.

Journal of Clinical Microbiology, October 1999, p. 3380-3383, Vol. 37, No. 10
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Biedenbach, D. J., Ross, J. E., Fritsche, T. R., Sader, H. S., Jones, R. N. (2007). Activity of Dalbavancin Tested against Staphylococcus spp. and {beta}-Hemolytic Streptococcus spp. Isolated from 52 Geographically Diverse Medical Centers in the United States. J. Clin. Microbiol. 45: 998-1004 [Abstract] [Full Text]  
  • Tikofsky, L. L., Zadoks, R. N. (2005). Cross-Infection Between Cats and Cows: Origin and Control of Streptococcus canis Mastitis in a Dairy Herd. J DAIRY SCI 88: 2707-2713 [Abstract] [Full Text]  
  • Kluka, E. A. (2004). Diagnosis: Brain Abscess with Early Pott Puffy Tumor. CLIN PEDIATR 43: 302-303  
  • Hashikawa, S., Iinuma, Y., Furushita, M., Ohkura, T., Nada, T., Torii, K., Hasegawa, T., Ohta, M. (2004). Characterization of Group C and G Streptococcal Strains That Cause Streptococcal Toxic Shock Syndrome. J. Clin. Microbiol. 42: 186-192 [Abstract] [Full Text]  
  • Zaoutis, T., Moore, L. S., Furness, K., Klein, J. D. (2001). In Vitro Activities of Linezolid, Meropenem, and Quinupristin-Dalfopristin against Group C and G Streptococci, Including Vancomycin-Tolerant Isolates. Antimicrob. Agents Chemother. 45: 1952-1954 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»