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Journal of Clinical Microbiology, November 1999, p. 3735-3737, Vol. 37, No. 11
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Candida Isolates from Neonates: Frequency of Misidentification and Reduced Fluconazole Susceptibility

Judith L. Rowen,1,dagger ,* Judy M. Tate,1 Nicole Nordoff,2 Lester Passarell,2 and Michael R. McGinnis2,dagger

Departments of Pediatrics1 and Pathology,2 University of Texas Medical Branch, Galveston, Texas 77555

Received 12 April 1999/Returned for modification 20 May 1999/Accepted 23 July 1999

Systemic candidiasis affects 1.6 to 4.5% of very low birth weight (<= 1,500 g) infants. A specimen archive of Candida strains from intensive care nurseries was created; it currently houses 98 isolates from 17 institutions. Eight isolates (8.2%) were misidentified at the referring institution. The MICs of fluconazole for seven isolates (7.1%, all non-C. albicans species, one misidentified initially) were >8 µg/ml.

* Corresponding author. Mailing address: Department of Pediatrics, University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555-0371. Phone: (409) 772-2798. Fax: (409) 747-1753. E-mail: jrowen{at}utmb.edu.

dagger Member of The Neonatal Candidiasis Study Group. Other group members who submitted isolates are Karen E. Shattuck, University of Texas Medical Branch, Galveston; Michael J. Horgan and Marilyn A. Kacica, Albany Medical College, Albany, N.Y.; Donna J. Fisher, Baystate Medical Center Children's Hospital, Springfield, Mass.; Michele Estabrook, Case Western Reserve University, Cleveland, Ohio; Paul L. Toubas, Children's Hospital of Oklahoma, Oklahoma City; Lisa Saiman, Babies & Children's Hospital, Columbia University, New York, N.Y.; E. Stephen Buescher and M. Gary Karlowicz, Eastern Virginia Medical School, Norfolk; Frederick Cox and Jatinder Bhatia, Medical College of Georgia, Augusta; William Albritton and Cindy McEvoy, Children's Hospital at Sacred Heart, Pensacola, Fla.; Gordon E. Schutze, University of Arkansas for Medical Sciences and Arkansas Children's Hospital, Little Rock; Peggy Weintrub, University of California, San Francisco; Mark J. Abzug, University of Colorado and The Children's Hospital, Denver; Mobeen H. Rathore and Ana Alvarez, University of Florida Health Science Center, Jacksonville; Gerard Rabalais and Kristin Bryant, University of Louisville School of Medicine, Louisville, Ky.; Roger Faix, University of Michigan, Ann Arbor; Catherine M. Bendel, University of Minnesota, Minneapolis; Sandor Feldman, University of Mississippi Medical Center, Jackson; and Wendy J. Watson, University of Rochester, Rochester, N.Y.

Journal of Clinical Microbiology, November 1999, p. 3735-3737, Vol. 37, No. 11
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


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