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Journal of Clinical Microbiology, December 1999, p. 4153-4155, Vol. 37, No. 12
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Analysis of GB Virus C Markers in Families Over Three Generations

Margaret Chen,1 Björn Fischler,2 Catharina Hultgren,1 Robert Halasz,1 Antal Nemeth,2 and Matti Sällberg1,*

Divisions of Clinical Virology and Basic Oral Science1 and Department of Pediatrics,2 Karolinska Institutet at Huddinge University Hospital, S-141 86 Huddinge, Sweden

Received 16 April 1999/Returned for modification 23 June 1999/Accepted 23 August 1999

GB virus C (GBV-C) markers were analyzed in two to three generations in three families with documented vertical transmission of GBV-C. None of the maternal grandparents had GBV-C markers, whereas the male spouses had GBV-C envelope 2 antibodies. Evidence was found for intrafamilial transmission but not for GBV-C transmission over three generations.

* Corresponding author. Mailing address: Division of Clinical Virology, F 68, Karolinska Institutet at Huddinge University Hospital, S-141 86 Huddinge, Sweden. Phone: 46-8-5858 7939. Fax: 46-8-5858 7933. E-mail: misg{at}labd01.hs.sll.se.

Journal of Clinical Microbiology, December 1999, p. 4153-4155, Vol. 37, No. 12
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.




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