This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Layani-Milon, M.-P.
Right arrow Articles by Lina, B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Layani-Milon, M.-P.
Right arrow Articles by Lina, B.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, June 1999, p. 1721-1726, Vol. 37, No. 6
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.

Incidence of Upper Respiratory Tract Mycoplasma pneumoniae Infections among Outpatients in Rhône-Alpes, France, during Five Successive Winter Periods

Marie-Paule Layani-Milon,* Isabelle Gras, Martine Valette, Jacques Luciani, Jean Stagnara, Michèle Aymard, and Bruno Lina

Laboratoire de Virologie du CHU et Groupe Régional d'Observation de la Grippe Rhône-Alpes, Hospices Civils de Lyon, Domaine Rockefeller, 69373 Lyon Cedex 08, France

Received 26 August 1998/Returned for modification 7 October 1998/Accepted 23 February 1999

In this prospective study, nasal swab samples from patients with acute respiratory infections were evaluated for the presence of Mycoplasma pneumoniae. This PCR-plus-hybridization-based detection was associated with the detection of other viral agents. During the five winter surveillance periods, 3,897 samples were collected by 75 medical practitioners participating in the Groupe Régional d'Observation de la Grippe surveillance network in Rhône-Alpes (France). M. pneumoniae was detected in 283 samples (7.3%); its rate of detection ranged from 10.1 to 2.0% over the five periods, and it was the second most frequently isolated pathogen during the survey, after influenza A. Three high-prevalence winters were observed, yielding an early winter peak of M. pneumoniae infection which was observed in all age groups. No statistically significant difference was detected between rates of infections in the different age groups, but M. pneumoniae infection was significantly related to lower respiratory tract infection during periods of high prevalence. This study defined the frequency of M. pneumoniae detection from nasal swab specimens in patients with acute respiratory infections, confirming its high prevalence and the presence of large outbreaks due to this pathogen.

* Corresponding author. Mailing address: Laboratoire de Virologie, Hospices Civils de Lyon, Domaine Rockefeller, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France. Phone: 33 478 77 70 29. Fax: 33 478 01 48 87. E-mail: layani{at}rockefeller.univ-lyon1.fr.

Journal of Clinical Microbiology, June 1999, p. 1721-1726, Vol. 37, No. 6
0095-1137/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Onozuka, D, Hashizume, M, Hagihara, A (2009). Impact of weather factors on Mycoplasma pneumoniae pneumonia. Thorax 64: 507-511 [Abstract] [Full Text]  
  • Dumke, R., Luck, P. C., Noppen, C., Schaefer, C., von Baum, H., Marre, R., Jacobs, E. (2006). Culture-Independent Molecular Subtyping of Mycoplasma pneumoniae in Clinical Samples.. J. Clin. Microbiol. 44: 2567-2570 [Abstract] [Full Text]  
  • Waites, K. B., Talkington, D. F. (2004). Mycoplasma pneumoniae and Its Role as a Human Pathogen. Clin. Microbiol. Rev. 17: 697-728 [Abstract] [Full Text]  
  • Esposito, S., Blasi, F., Bosis, S., Droghetti, R., Faelli, N., Lastrico, A., Principi, N. (2004). Aetiology of acute pharyngitis: the role of atypical bacteria. J Med Microbiol 53: 645-651 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»