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Journal of Clinical Microbiology, January 2000, p. 431-433, Vol. 38, No. 1
Institute of Parasitology and
Zoology1 and Institute of
Virology,2 University of Veterinary
Medicine, A-1210 Vienna, Schönbrunner Tiergarten Ges.m.b.H.,
A-1130 Vienna,3 and Department of
Medical Parasitology, Clinical Institute of Hygiene, University of
Vienna, A-1095 Vienna,4 Austria
Received 25 January 1999/Returned for modification 16 March
1999/Accepted 19 October 1999
In this paper, a serological assay for the detection of antibodies
to Capillaria hepatica, a zoonotic parasite, is described. In the past, the only way of detecting Capillaria hepatica
was to perform a liver biopsy. The indirect immunofluorescence (IIF) assay, based on liver sections of naturally infected mice and human
serum samples, is suitable for detecting early stages of human
infections and for screening purposes. No cross-reactivity with other
parasitic infections was detected. We have applied the IIF assay to
serum samples of 60 employees of the Zoological Garden of Vienna,
Schönbrunn, Austria, and found one positive and one questionable sample.
0095-1137/0/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.
Serological Detection of Capillaria
hepatica by Indirect Immunofluorescence Assay
*
Corresponding author. Mailing address: Institute of
Parasitology and Zoology, University of Veterinary Medicine,
Veterinärplatz 1, A-1210 Vienna, Austria. Phone: 43 1 25077 2220. Fax: 43 1 25077 2290. E-mail:
Martina.Juncker{at}vu-wien.ac.at.
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