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Journal of Clinical Microbiology, December 2000, p. 4653-4654, Vol. 38, No. 12
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Cryptic Genetic Diversity in Dientamoeba fragilis

Jeanette A. Johnson1 and C. Graham Clark2,*

Department of Microbiology, East Surrey Hospital, Redhill, Surrey RH1 5RH,1 and Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT,2 England

Received 5 May 2000/Returned for modification 10 July 2000/Accepted 18 September 2000

Uncertainty surrounding the role of Dientamoeba fragilis in human disease could be due in part to the existence of pathogenic and nonpathogenic variants. Evidence for two genetically distinct forms was obtained using PCR-restriction fragment length polymorphism analysis of ribosomal genes. Future studies in humans will need to take D. fragilis diversity into account.

* Corresponding author. Mailing address: Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England. Phone: 44-207-927-2350. Fax: 44-207-636-8739. E-mail: graham.clark{at}lshtm.ac.uk.

Journal of Clinical Microbiology, December 2000, p. 4653-4654, Vol. 38, No. 12
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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