This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Frühwirth, M.
Right arrow Articles by Mutz, I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Frühwirth, M.
Right arrow Articles by Mutz, I.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, May 2000, p. 1804-1806, Vol. 38, No. 5
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Distribution of Rotavirus VP4 Genotypes and VP7 Serotypes among Nonhospitalized and Hospitalized Patients with Gastroenteritis and Patients with Nosocomially Acquired Gastroenteritis in Austria

M. Frühwirth,1,* S. Brösl,2 H. Ellemunter,1 I. Moll-Schüler,3 A. Rohwedder,4 and I. Mutz2

Department of Pediatrics, University Hospital, Innsbruck,1 Children's Hospital, Leoben,2 and Wyeth-Lederle, Vienna,3 Austria, and Institute for Microbiology and Virology, Bochum, Germany4

Received 23 August 1999/Returned for modification 8 December 1999/Accepted 21 February 2000

To assess the potential benefits of a reassortant tetravalent rotavirus vaccine, we investigated stool specimens from children in three different groups by reverse transcription-PCR (RT-PCR) for rotavirus G and P types: (i) children not hospitalized with community-acquired rotavirus-acute gastroenteritis (RV-AGE), (ii) children hospitalized for RV-AGE, and (iii) children with nosocomially acquired RV-AGE. From a total of 553 samples investigated, 335 were positive by enzyme-linked immunosorbent assay, of which 294 (88%) were positive by RT-PCR. Among the RT-PCR-positive samples, the predominant types were G1P[8] (84%), followed by G4P[8] (9%) and G3P[8] (2%). No differences between the three groups were observed, suggesting that community vaccination will diminish the most cost-relevant cases of hospitalizations and nosocomial infections.

* Corresponding author. Mailing address: Department of Pediatrics, Innsbruck, University Hospital, Anichstrasse 35, A-6020 Innsbruck, Austria. Phone: 43-512-504-3501. Fax: 43-512-504-3484. E-mail: Martin.Fruehwirth{at}uibk.ac.at.

Journal of Clinical Microbiology, May 2000, p. 1804-1806, Vol. 38, No. 5
0095-1137/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Fischer, T. K., Eugen-Olsen, J., Pedersen, A. G., Molbak, K., Bottiger, B., Rostgaard, K., Nielsen, N. M. (2005). Characterization of Rotavirus Strains in a Danish Population: High Frequency of Mixed Infections and Diversity within the VP4 Gene of P[8] Strains. J. Clin. Microbiol. 43: 1099-1104 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»