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Journal of Clinical Microbiology, July 2000, p. 2763-2765, Vol. 38, No. 7
0095-1137/00/$04.00+0

Evaluation of the Binax and Biotest Urinary Antigen Kits for Detection of Legionnaires' Disease Due to Multiple Serogroups and Species of Legionella

Robert F. Benson,1,* Patrick W. Tang,2 and Barry S. Fields1

Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia,1 and Ministry of Health and Long Term Care, Toronto, Ontario, Canada2

Received 11 January 2000/Returned for modification 23 March 2000/Accepted 1 May 2000

The Binax and the Biotest urinary antigen kits for the detection of Legionnaires' disease caused by organisms other than Legionella pneumophila were compared by testing 45 urine samples from non-Legionella pneumophila serogroup 1 patients previously positive in a broad-spectrum enzyme-linked immunosorbent assay (ELISA). Eighteen were positive with the Binax kit, and 13 were positive with the Biotest. Although neither kit is as sensitive as ELISA, these results extend the number of serogroups and species of Legionella that can be diagnosed with the Binax or Biotest kit.

* Corresponding author. Mailing address: Respiratory Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Mailstop GO3, Centers for Disease Control and Prevention, Atlanta, GA 30333. Phone: (404) 639-3563. Fax: (404) 639-4215. E-mail: REB3{at}CDC.GOV.

Journal of Clinical Microbiology, July 2000, p. 2763-2765, Vol. 38, No. 7
0095-1137/00/$04.00+0


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