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Journal of Clinical Microbiology, October 2001, p. 3740-3742, Vol. 39, No. 10
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.10.3740-3742.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Comparative Performance of Herpes Simplex Virus Type 2-Specific Serologic Assays from Meridian Diagnostics and MRL Diagnostics

Julie A. Ribes,1,2,* Marie Hayes,1,dagger Angela Smith,1,2 Jeffrey L. Winters,2 and Doris J. Baker1

Departments of Clinical Laboratory Sciences1 and Pathology and Laboratory Medicine,2 University of Kentucky, Lexington, Kentucky 40536-0298

Received 11 December 2000/Returned for modification 18 March 2001/Accepted 23 July 2001

MRL Diagnostics and Meridian Diagnostics have recently designed herpes simplex virus type 2 (HSV-2)-specific enzyme immunoassays for HSV-2 antibody detection. Blood donor sera were assayed for HSV-2 antibodies by both methods. The sensitivity, specificity, and efficiency were 97.9, 95.4, and 95.9% for the MRL assay and 83.2, 98.2, and 95.5% for the Meridian assay, respectively.

* Corresponding author. Mailing address: University of Kentucky, Department of Pathology and Laboratory Medicine, MS-117 Medical Center, 800 Rose St., Lexington, KY 40536-0298. Phone: (859) 323-1368. Fax: (859) 323-5054. E-mail: jaribes{at}uky.edu.

dagger Present address: Boston IVF, Waltham, MA 02451.

Journal of Clinical Microbiology, October 2001, p. 3740-3742, Vol. 39, No. 10
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.10.3740-3742.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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