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Journal of Clinical Microbiology, October 2001, p. 3801-3802, Vol. 39, No. 10
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.10.3801-3802.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Value of Throat Swab in Diagnosis of Melioidosis

Vanaporn Wuthiekanun,1 Yupin Suputtamongkol,2 A. J. H. Simpson,1,3,dagger Panida Kanaphun,4 and N. J. White1,3,*

Faculty of Tropical Medicine1 and Faculty of Medicine Siriraj Hospital,2 Mahidol University, Bangkok, and Department of Paediatrics, Sappasitprasong Hospital, Ubon Ratchathani,4 Thailand, and Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford, United Kingdom3

Received 14 March 2001/Returned for modification 13 May 2001/Accepted 23 July 2001

Throat swab (TS) cultures were performed for 1,011 patients with melioidosis and 3,524 healthy subjects or patients with other diseases. The specificity of TS culture for the diagnosis of melioidosis was 100%, and the overall sensitivity was 36% (24% for sputum-negative patients and 79% for sputum-positive patients). Direct plating of the TS specimen on Ashdown's medium was rapid (colonies were usually evident within 24 h) but only 63% sensitive compared to the results of primary culture in a selective broth. A throat swab should be cultured in all cases of suspected melioidosis.

* Corresponding author. Mailing address: Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Rd., Bangkok 10400, Thailand. Phone: 66 2 246 0832. Fax: 66 2 246 7795. E-mail: fnnjw{at}diamond.mahidol.ac.th.

dagger Present address: Department of Medical Microbiology, Royal Free Hospital, London, United Kingdom.

Journal of Clinical Microbiology, October 2001, p. 3801-3802, Vol. 39, No. 10
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.10.3801-3802.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

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