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Journal of Clinical Microbiology, November 2001, p. 4178-4180, Vol. 39, No. 11
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.11.4178-4180.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Identification of Aichi Virus Infection by Measurement of Immunoglobulin Responses in an Enzyme-Linked Immunosorbent Assay

Teruo Yamashita,* Miyabi Ito, Hideaki Tsuzuki, and Kenji Sakae

Department of Microbiology, Aichi Prefectural Institute of Public Health, Nagare 7-6, Tsuji-machi, Kita-ku, Nagoya 462-8576, Japan

Received 23 April 2001/Returned for modification 30 June 2001/Accepted 5 August 2001

Using inhibitory enzyme-linked immunosorbent assay, seroconversions to Aichi virus were detected in 24 (42.9%) of 56 patients with gastroenteritis in six outbreaks. Virus-specific immunoglobulin M (IgM) was detected in convalescent-phase sera from 7 of 24 patients. Of the other 17 patients, 12 developed a significant increase in both IgA and IgG levels and 5 developed a significant increase in IgG alone.

* Corresponding author. Mailing address: Department of Microbiology, Aichi Prefectural Institute of Public Health, Nagare 7-6, Tsuji-machi, Kita-ku, Nagoya, Aichi 462-8576, Japan. Phone: 81-52-910-5674. Fax: 81-52-913-3641. E-mail: tyamashita{at}hi-ho.ne.jp.

Journal of Clinical Microbiology, November 2001, p. 4178-4180, Vol. 39, No. 11
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.11.4178-4180.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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