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Journal of Clinical Microbiology, November 2001, p. 4213-4218, Vol. 39, No. 11
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.11.4213-4218.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Isolation of a Nodulisporium Species from a Case of Cerebral Phaeohyphomycosis

P. Umabala,1 V. Lakshmi,1,* A. R. Murthy,2 V. S. S. V. Prasad,2 C. Sundaram,3 and H. Beguin4

Departments of Microbiology,1 Neurosurgery,2 and Pathology,3 Nizam's Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India, and Scientific Institute of Public Health, BCCM/IHEM Culture Collection, Brussels, Belgium4

Received 16 March 2001/Returned for modification 30 May 2001/Accepted 8 July 2001

A fungal infection of the brain of a 55-year-old male patient is reported. The lesion and involved fungus were located exclusively in the right medial temporo-parietal region. The patient was successfully treated with surgical resection of the lesion and antifungal chemotherapy. Few pathogenic dematiaceous fungi exhibit neurotropism and can cause primary infection in the central nervous system (CNS). The etiological agent is described as a Nodulisporium species. To date Nodulisporium has never been reported as an agent of CNS infection in humans.

* Corresponding author. Mailing address: Department of Microbiology, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad-500 082, Andhra Pradesh, India. Phone: 91 040 425 6478. Fax: 91 040 331 0076. E-mail: lgorthi{at}hotmail.com.

Journal of Clinical Microbiology, November 2001, p. 4213-4218, Vol. 39, No. 11
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.11.4213-4218.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.




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