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Journal of Clinical Microbiology, December 2001, p. 4523-4525, Vol. 39, No. 12
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.12.4523-4525.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Evaluation of ColorPAC Giardia/Cryptosporidium Rapid Assay and ProSpecT Giardia/Cryptosporidium Microplate Assay for Detection of Giardia and Cryptosporidium in Fecal Specimens

M. T. Katanik,1 S. K. Schneider,2 J. E. Rosenblatt,2 G. S. Hall,1 and G. W. Procop1,*

Section of Clinical Microbiology, Cleveland Clinic Foundation, Cleveland, Ohio,1 and Department of Clinical Microbiology, Mayo Clinic Foundation, Rochester, Minnesota2

Received 27 June 2001/Returned for modification 7 August 2001/Accepted 17 September 2001

Detection of Giardia and Cryptosporidium in clinical stool specimens using the ColorPAC and ProSpecT enzyme immunoassays revealed 98.7% agreement for Giardia detection and 98.1% agreement for Cryptosporidium detection. Sensitivities were uniformly 100%. The specificities of the ColorPAC immunoassay for Giardia and Cryptosporidium detection were 100 and 99.5%, respectively, and those for the ProSpecT assay were 98.4 and 98.6%, respectively. The false-positive reactions with the ProSpecT assay occurred with specimens that were grossly bloody.

* Corresponding author. Mailing address: Department of Pathology, Mailstop L40, Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, OH 44195. Phone: (216) 444-5879. Fax: (216) 445-6984. E-mail: procopg{at}ccf.org.

Journal of Clinical Microbiology, December 2001, p. 4523-4525, Vol. 39, No. 12
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.12.4523-4525.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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