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Journal of Clinical Microbiology, December 2001, p. 4532-4534, Vol. 39, No. 12
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.12.4532-4534.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Evaluation of Two Enzyme Immunoassays for Detection of Human Rotaviruses in Fecal Specimens

Bodo R. Eing,1,* Guenter May,1 Horst G. Baumeister,2 and Joachim E. Kühn1

Institute of Medical Microbiology, Clinical Virology, University of Muenster,1 and Institute of Public Health, North Rhine-Westphalia,2 Muenster, Germany

Received 2 May 2001/Returned for modification 23 July 2001/Accepted 17 September 2001

The two assays evaluated in this study (the Ridascreen rotavirus and the Pathfinder rotavirus) exhibited comparable sensitivities (100%) but highly divergent positive predictive values (93.74 and 57.7%, respectively) when compared on 393 specimens. This difference should be considered when using these tests on collectives with an unknown or low prevalence.

* Corresponding author. Mailing address: Institute of Medical Microbiology, Clinical Virology, von-Stauffenberg-Str. 36, 48151 Muenster, Germany. Phone: (49) 251 7793 111. Fax: (49) 251 7793 104. E-mail: eingb{at}uni-muenster.de.

Journal of Clinical Microbiology, December 2001, p. 4532-4534, Vol. 39, No. 12
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.12.4532-4534.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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