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Journal of Clinical Microbiology, December 2001, p. 4541-4543, Vol. 39, No. 12
0095-1137/01/$04.00+0 DOI: 10.1128/JCM.39.12.4541-4543.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.
Association of the Urease Gene with Enterohemorrhagic
Escherichia coli Strains Irrespective of Their
Serogroups
Masayuki
Nakano,1
Tetsuya
Iida,1,*
Makoto
Ohnishi,2
Ken
Kurokawa,3
Akira
Takahashi,4
Teizo
Tsukamoto,5
Teruo
Yasunaga,3
Tetsuya
Hayashi,2 and
Takeshi
Honda1
Department of Bacterial Infections, Research Institute for
Microbial Diseases, Osaka University,1 and
Genome Information Research Center, Osaka University, Suita,
Osaka,3 Department of Microbiology,
Miyazaki Medical College, Kiyotake,
Miyazaki,2 Department of Nutrition,
School of Medicine, Tokushima University, Tokushima,
Tokushima,4 and Osaka Prefectural
Institute of Public Health, Osaka,5 Japan
Received 24 May 2001/Returned for modification 3 September
2001/Accepted 19 September 2001
Among various diarrheagenic Escherichia coli strains
from clinical sources, we found that the urease gene was specifically associated with enterohemorrhagic E. coli (EHEC) strains
irrespective of their serogroups. The results suggest that the urease
gene can be a useful genetic marker for the detection of EHEC strains and for the diagnosis of infections caused by EHEC strains in the
clinical situation.
*
Corresponding author. Mailing address: Department of
Bacterial Infections, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan. Phone: 81-6-6879-8278. Fax: 81-6-6879-8277. E-mail:
iida{at}biken.osaka-u.ac.jp.
Journal of Clinical Microbiology, December 2001, p. 4541-4543, Vol. 39, No. 12
0095-1137/01/$04.00+0 DOI: 10.1128/JCM.39.12.4541-4543.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.
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