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Journal of Clinical Microbiology, February 2001, p. 820-822, Vol. 39, No. 2
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.2.820-822.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Infection of Central Nervous System by Motile Enterococcus: First Case Report

Asok Kurup,1,* Wen Sim Nancy Tee,2 Liat Hui Loo,3 and Raymond Lin3

Departments of Internal Medicine1 and of Pathology,2 Singapore General Hospital, Singapore 169608, and Clinical Microbiology Laboratory, KK Women's and Children's Hospital, Singapore 2298993

Received 25 October 2000/Returned for modification 3 November 2000/Accepted 11 November 2000

A 66-year-old man with four indwelling ventriculoperitoneal shunts for multiloculated hydrocephalus from a complicated case of meningitis a year before developed shunt infection based on a syndrome of fever, drowsiness, and cerebrospinal fluid neutrophil pleocytosis in the background of repeated surgical manipulation to relieve successive shunt blockages. The cerebrospinal fluid culture, which yielded a motile Enterococcus species, was believed to originate from the gut. This isolate was lost in storage and could not be characterized further. The patient improved with vancomycin and high-dose ampicillin therapy. He relapsed a month later with Enterococcus gallinarum shunt infection, which responded to high-dose ampicillin and gentamicin therapy. This is probably the first case report of motile Enterococcus infection of the central nervous system.

* Corresponding author. Mailing address: 3843G Miramar St., La Jolla, CA 92037. Phone: (619) 543-8080. Fax: (619) 298-0177. E-mail: akurup99{at}yahoo.com.

Journal of Clinical Microbiology, February 2001, p. 820-822, Vol. 39, No. 2
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.2.820-822.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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