This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Luu, L. N.
Right arrow Articles by Anderson, J. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Luu, L. N.
Right arrow Articles by Anderson, J. B.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, April 2001, p. 1657-1660, Vol. 39, No. 4
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.4.1657-1660.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Multilocus Genotyping Indicates that the Ability To Invade the Bloodstream Is Widespread among Candida albicans Isolates

Lien N. Luu, Leah E. Cowen,* Caroline Sirjusingh, Linda M. Kohn, and James B. Anderson

Department of Botany, University of Toronto, Mississauga, Ontario, Canada L5L 1C6

Received 16 August 2000/Returned for modification 29 November 2000/Accepted 9 February 2001

Multilocus genotyping was used to compare populations of Candida albicans from oral mucosa and blood. No significant differences in allele frequencies between the two samples were detected, and in a dendrogram of genotypic similarities, genotypes from both types of samples were finely interspersed. This is evidence for widespread distribution of invasive potential.


* Corresponding author. Mailing address: Department of Botany, University of Toronto, 3359 Mississauga Rd. North, Mississauga, Ontario, Canada L5L 1C6. Phone: (905) 828-5338. Fax: (905) 828-3792. E-mail: lcowen{at}credit.erin.utoronto.ca.


Journal of Clinical Microbiology, April 2001, p. 1657-1660, Vol. 39, No. 4
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.4.1657-1660.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.



This article has been cited by other articles:

  • Odds, F. C., Jacobsen, M. D. (2008). Multilocus Sequence Typing of Pathogenic Candida Species. Eukaryot Cell 7: 1075-1084 [Full Text]  
  • Dalle, F., Dumont, L., Franco, N., Mesmacque, D., Caillot, D., Bonnin, P., Moiroux, C., Vagner, O., Cuisenier, B., Lizard, S., Bonnin, A. (2003). Genotyping of Candida albicans Oral Strains from Healthy Individuals by Polymorphic Microsatellite Locus Analysis. J. Clin. Microbiol. 41: 2203-2205 [Abstract] [Full Text]  
  • Lott, T. J., Fundyga, R. E., Brandt, M. E., Harrison, L. H., Sofair, A. N., Hajjeh, R. A., Warnock, D. W. (2003). Stability of Allelic Frequencies and Distributions of Candida albicans Microsatellite Loci from U.S. Population-Based Surveillance Isolates. J. Clin. Microbiol. 41: 1316-1321 [Abstract] [Full Text]  
  • DOCZI, I., DOSA, E., HAJDU, E., NAGY, E. (2002). Aetiology and antifungal susceptibility of yeast bloodstream infections in a Hungarian university hospital between 1996 and 2000. J Med Microbiol 51: 677-681 [Abstract] [Full Text]  
  • Cowen, L. E., Nantel, A., Whiteway, M. S., Thomas, D. Y., Tessier, D. C., Kohn, L. M., Anderson, J. B. (2002). Population genomics of drug resistance in Candida albicans. Proc. Natl. Acad. Sci. USA 99: 9284-9289 [Abstract] [Full Text]  
  • Bougnoux, M.-E., Morand, S., d'Enfert, C. (2002). Usefulness of Multilocus Sequence Typing for Characterization of Clinical Isolates of Candida albicans. J. Clin. Microbiol. 40: 1290-1297 [Abstract] [Full Text]  
  • Botterel, F., Desterke, C., Costa, C., Bretagne, S. (2001). Analysis of Microsatellite Markers of Candida albicans Used for Rapid Typing. J. Clin. Microbiol. 39: 4076-4081 [Abstract] [Full Text]