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Journal of Clinical Microbiology, April 2001, p. 1657-1660, Vol. 39, No. 4
0095-1137/01/$04.00+0 DOI: 10.1128/JCM.39.4.1657-1660.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.
Multilocus Genotyping Indicates that the Ability To
Invade the Bloodstream Is Widespread among Candida
albicans Isolates
Lien N.
Luu,
Leah E.
Cowen,*
Caroline
Sirjusingh,
Linda M.
Kohn, and
James B.
Anderson
Department of Botany, University of Toronto,
Mississauga, Ontario, Canada L5L 1C6
Received 16 August 2000/Returned for modification 29 November
2000/Accepted 9 February 2001
Multilocus genotyping was used to compare populations of
Candida albicans from oral mucosa and blood. No significant
differences in allele frequencies between the two samples were
detected, and in a dendrogram of genotypic similarities, genotypes from
both types of samples were finely interspersed. This is evidence for widespread distribution of invasive potential.
*
Corresponding author. Mailing address: Department of
Botany, University of Toronto, 3359 Mississauga Rd. North, Mississauga, Ontario, Canada L5L 1C6. Phone: (905) 828-5338. Fax: (905) 828-3792. E-mail: lcowen{at}credit.erin.utoronto.ca.
Journal of Clinical Microbiology, April 2001, p. 1657-1660, Vol. 39, No. 4
0095-1137/01/$04.00+0 DOI: 10.1128/JCM.39.4.1657-1660.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.
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