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Journal of Clinical Microbiology, July 2001, p. 2695-2699, Vol. 39, No. 7
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.7.2695-2699.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Comparison of Serogroup W-135 Meningococci Isolated in Sweden during a 23-Year Period and Those Associated with a Recent Hajj Pilgrimage

Paula Mölling,1,* Anders Bäckman,1 Per Olcén,1 and Hans Fredlund1,2

National Reference Laboratory for Pathogenic Neisseria1 and Unit for Infectious Disease Control,2 Department of Clinical Microbiology & Immunology, Örebro Medical Centre Hospital, Örebro, Sweden

Received 5 December 2000/Returned for modification 26 February 2001/Accepted 7 April 2001

An outbreak of serogroup W-135 meningococcal disease was reported among pilgrims returning from the annual hajj (pilgrimage to Mecca) in mid-March 2000. Molecular characterization was used to investigate the similarity of the hajj-associated W-135 strains with those isolated in Sweden during a 23-year period (1978 to 2000). The same hajj-associated genosubtype, genosubtype P1.5,2,36b, has been documented in Sweden since 1979, while pulsed-field gel electrophoresis and the sulfadiazine resistance of the W-135 isolates indicated that the outbreak was probably due to a new clone of W-135 meningococci.

* Corresponding author. Mailing address: Department of Clinical Microbiology & Immunology, Örebro Medical Centre Hospital, SE-701 85 Örebro, Sweden. Phone: 46-19-602 15 20. Fax: 46-19-12 74 16. E-mail: paula.molling{at}orebroll.se.

Journal of Clinical Microbiology, July 2001, p. 2695-2699, Vol. 39, No. 7
0095-1137/01/$04.00+0   DOI: 10.1128/JCM.39.7.2695-2699.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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