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Journal of Clinical Microbiology, July 2002, p. 2629-2631, Vol. 40, No. 7
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.7.2629-2631.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Molecular and Seroepidemiological Evidence of Canine Calicivirus Infections in Japan

Masami Mochizuki,1* Michiru Hashimoto,1 Frank Roerink,2 Yukinobu Tohya,3 Yuichi Matsuura,4 and Nobuo Sasaki5

Laboratory of Clinical Microbiology,1 Tsukuba Central Laboratories, Kyoritsu Seiyaku Corporation, 1-12-4 Kudankita, Chiyoda-ku, Tokyo 102-0073,2 Departments of Veterinary Microbiology,3 Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657,5 Laboratory of Veterinary Microbiology, Department of Veterinary Medicine, Faculty of Agriculture, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan4

Received 19 December 2001/ Returned for modification 10 March 2002/ Accepted 31 March 2002

Calicivirus infection of dogs was epidemiologically investigated by using canine calicivirus (CaCV) strain 48 as a reference. Similar RNA polymerase gene sequences and neutralizing antibodies against CaCV were detected in 1.7% of clinical specimens and 57% of serum samples, respectively, suggesting a high prevalence of CaCV in dog populations.

* Corresponding author. Mailing address: Laboratory of Clinical Microbiology, Kyoritsu Seiyaku Corporation, 1-12-4 Kudankita, Chiyoda-ku, Tokyo 102-0073, Japan. Phone: 81-3-3264-7117. Fax: 81-3-3264-6094. E-mail: msmmchzk{at}mb.infoweb.ne.jp.

Journal of Clinical Microbiology, July 2002, p. 2629-2631, Vol. 40, No. 7
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.7.2629-2631.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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