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Journal of Clinical Microbiology, August 2002, p. 3064-3065, Vol. 40, No. 8
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.8.3064-3065.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Preliminary Evaluation of an Immunochromatographic Strip Test for Specific Treponema pallidum Antibodies

Pinar Zarakolu,1 Ian Buchanan,2 Milton Tam,2 Kim Smith,3 and Edward W. Hook III3,4*

Section of Infectious Diseases, Department of Medicine, School of Medicine, Hacettepe University, Ankara, Turkey,1 Program for Appropriate Technology in Health, Seattle, Washington,2 Department of Medicine, University of Alabama at Birmingham School of Medicine,3 Sexually Transmitted Diseases Control Program, Jefferson County Department of Health, Birmingham, Alabama4

Received 24 September 2001/ Returned for modification 21 December 2001/ Accepted 1 April 2002

We evaluated a prototype immunochromatographic strip (ICS) test for qualitative detection of Treponema pallidum antibodies in 353 sera from 157 patients. For sera from 43 syphilis patients, the ICSs were reactive, while for sera from 114 patients without syphilis, including 22 with biologically false-positive Rapid Plasma Reagin test results, the ICSs were nonreactive. The ICS test may expand the available options for serological testing for syphilis.

* Corresponding author. Mailing address: University of Alabama at Birmingham, 703 19th St. South, ZRB 242, Birmingham, AL 35294-0007. Phone: (205) 934-4204. Fax: (205) 975-7764. E-mail: ehook{at}uab.edu.

Journal of Clinical Microbiology, August 2002, p. 3064-3065, Vol. 40, No. 8
0095-1137/02/$04.00+0     DOI: 10.1128/JCM.40.8.3064-3065.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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