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Journal of Clinical Microbiology, December 2003, p. 5738-5740, Vol. 41, No. 12
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.12.5738-5740.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Most Human Isolates of Mycobacterium avium Mav-A and Mav-B Are Strong Producers of Hemolysin, a Putative Virulence Factor

Laura Rindi, Daniela Bonanni, Nicoletta Lari, and Carlo Garzelli*

Dipartimento di Patologia Sperimentale, Biotecnologie Mediche, Infettivologia, ed Epidemiologia, Università di Pisa, I-56127 Pisa, Italy

Received 9 May 2003/ Returned for modification 1 August 2003/ Accepted 3 September 2003

Hemolysin was quantified in 58 isolates of Mycobacterium avium from human, animal, and environmental sources. Human Mav-A and Mav-B isolates were the strongest producers; in contrast, animal and environmental Mav-A isolates and human, animal, and environmental Mav-C organisms were low-level producers. Hemolysin production was not restricted to isolates causing invasive infections.

* Corresponding author. Mailing address: Dipartimento di Patologia Sperimentale, Biotecnologie Mediche, Infettivologia ed Epidemiologia, Università di Pisa, Via San Zeno, 35/39, I-56127 Pisa, Italy. Phone: 39-0-50 2213670. Fax: 39-0-50 2213671. E-mail: garzelli{at}biomed.unipi.it.

Journal of Clinical Microbiology, December 2003, p. 5738-5740, Vol. 41, No. 12
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.12.5738-5740.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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