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Journal of Clinical Microbiology, May 2003, p. 2197-2200, Vol. 41, No. 5
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.5.2197-2200.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Extended-Spectrum ß-Lactamase Enzymes in Clinical Isolates of Enterobacter Species from Lagos, Nigeria

I. E. Aibinu,1* V. C. Ohaegbulam,1 E. A. Adenipekun,1 F. T. Ogunsola,1 T. O. Odugbemi,1 and B. J. Mee2

Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, P.M.B 12003, Lagos, Nigeria,1 Department of Microbiology, School of Biomedical and Chemical Sciences, The University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands 6009, Western Australia, Australia2

Received 6 November 2002/ Returned for modification 11 December 2002/ Accepted 10 February 2003

Over a 9-month period, 8 of 40 nonduplicate isolates of Enterobacter spp. producing extended-spectrum ß-lactamase (ESBL) were detected for the first time from two hospitals in Lagos, Nigeria. Microbiologic and molecular analysis confirmed the presence of ESBL. Only four isolates transferred ESBL resistance as determined by the conjugation test, and pulsed-field gel electrophoresis showed genetically unrelated isolates.


* Corresponding author. Mailing address: Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, P.M.B 12003, Lagos, Nigeria. Phone: 234 803 3377345. Fax: 234 01 5851432. E-mail: ibaibinu{at}yahoo.com.


Journal of Clinical Microbiology, May 2003, p. 2197-2200, Vol. 41, No. 5
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.5.2197-2200.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.




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