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Journal of Clinical Microbiology, July 2003, p. 3433-3435, Vol. 41, No. 7
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.7.3433-3435.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Neonatal Sepsis Caused by Streptococcus bovis Variant (Biotype II/2): Report of a Case and Review

Patrick J. Gavin,1,2,3* Richard B. Thomson, Jr.,2,3 Show-Jen Horng,2 and Ram Yogev1,3

Division of Infectious Diseases, Children's Memorial Hospitalthe,1 Feinberg School of Medicine, Northwestern University, Chicago, and the,3 Department of Pathology and Laboratory Medicine, Evanston Northwestern Healthcare, Evanston, Illinois2

Received 23 December 2002/ Returned for modification 16 February 2003/ Accepted 17 March 2003

Streptococcus bovis is an uncommon cause of infection in neonates. However, S. bovis is capable of causing fulminant neonatal sepsis or meningitis that is indistinguishable clinically from that caused by group B streptococcus. S. bovis and S. bovis variant (sometimes referred to as S. bovis biotypes I and II, respectively) are phenotypically similar but may be differentiated by expanded testing. In adults, specific associations between disease states and different biotypes of S. bovis are apparent. No data exist on possible differences or clinical relevance of neonatal infection caused by different biotypes or newer species of S. bovis. We report a 3-day-old neonate with bacteremia and meningitis caused by S. bovis variant (S. bovis biotype II/2) and review the literature.


* Corresponding author. Mailing address: Department of Pathology and Laboratory Medicine, Evanston Northwestern Healthcare, 2650 Ridge Ave., Room 1936, Evanston, IL 60201. Phone: (847) 570-2744. Fax: (847) 733-5314. E-mail: pgavin{at}enh.org.


Journal of Clinical Microbiology, July 2003, p. 3433-3435, Vol. 41, No. 7
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.7.3433-3435.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.




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