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Journal of Clinical Microbiology, September 2003, p. 4451-4453, Vol. 41, No. 9
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.9.4451-4453.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Genital Human Papillomavirus Genotypes in Northwestern Tanzania

Philippe Mayaud,1* Helen A. Weiss,1 Charles J. N. Lacey,2 Dilbinder K. Gill,2,{dagger} and David C. W. Mabey1

Department of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London WC1E 7HT,1 Faculty of Medicine, Imperial College London, London W2 1PG, United Kingdom2

Received 6 November 2002/ Returned for modification 20 February 2003/ Accepted 10 June 2003

Using MY09-MY11 PCR and human papillomavirus (HPV) typing by reverse blot hybridization, we found a 34% cervical HPV prevalence among 561 pregnant women in Tanzania. One hundred three of 123 women (84%) with typeable samples harbored high-risk oncogenic strains. HPV type 16 (HPV-16) was the most prevalent subtype (18%) among HPV-infected women and among women with cervical neoplasia (3 of 19). A multivalent vaccine for HPV-16, -18, -31, -33, and -35 would be necessary to prevent 50% of the neoplasia in this population.


* Corresponding author. Mailing address: Department of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, Keppel St., London WC1E 7HT, United Kingdom. Phone: 44 (0)207 927 2291. Fax: 44 (0)207 637 4314. E-mail: philippe.mayaud{at}lshtm.ac.uk.

{dagger} Present address: IAVI Core Laboratory, Imperial College London, St. Steven's Centre, Chelsea & Westminster Hospital, London SW10 9NH, United Kingdom.


Journal of Clinical Microbiology, September 2003, p. 4451-4453, Vol. 41, No. 9
0095-1137/03/$08.00+0     DOI: 10.1128/JCM.41.9.4451-4453.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.




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