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Journal of Clinical Microbiology, January 2004, p. 431-434, Vol. 42, No. 1
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.1.431-434.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Molecular Epidemiology of Disease Due to Mycobacterium bovis in Humans in the United Kingdom

Andrea L. Gibson,1* Glyn Hewinson,2 Tony Goodchild,2 Brian Watt,3,{dagger} Alistair Story,4 Jacqueline Inwald,2 and Francis A. Drobniewski1

Mycobacterium Reference Unit, Health Protection Agency, and Department of Microbiology, Guy's, King's and St Thomas' School of Medicine, King's College Hospital (Dulwich), East Dulwich Grove, London, SE22 8QF,1 Veterinary Laboratory Agency, Weybridge, New Haw, Surrey KT15 3NB,2 Scottish Mycobacteria Reference Laboratory, Royal Infirmary, Little France, Edinburgh EH16 4SA,3 HPA, Communicable Disease Surveillance Centre, Colindale, London NW9 5EQ, United Kingdom4

Received 2 May 2003/ Returned for modification 13 June 2003/ Accepted 12 September 2003

Mycobacterium bovis is the causative agent of bovine tuberculosis, with a wide host range. Fifty human M. bovis isolates were typed using spoligotyping and variable number tandem repeats (VNTR). Fifteen of these spoligotypes have not yet been recorded in cattle. The predominant spoligotype in humans and cattle was subdivided by VNTR.

* Corresponding author. Mailing address: Mycobacterium Reference Unit, Health Protection Agency, Dulwich Hospital, East Dulwich Grove, London SE22 8QF, United Kingdom. Phone: 0208 693 1312. Fax: 0207 346 6477. E-mail: andreagibson78{at}hotmail.com.

{dagger} Present address: Silverburn House, by Penicuik, Midlothian, EH26 9LF, United Kingdom.

Journal of Clinical Microbiology, January 2004, p. 431-434, Vol. 42, No. 1
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.1.431-434.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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