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Journal of Clinical Microbiology, October 2004, p. 4853-4855, Vol. 42, No. 10
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.10.4853-4855.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Performance of the Binax NOW Streptococcus pneumoniae Urinary Antigen Assay for Diagnosis of Pneumonia in Children with Underlying Pulmonary Diseases in the Absence of Acute Pneumococcal Infection

David Navarro,1 Leonor García-Maset,2 Concepción Gimeno,1 Amparo Escribano,2 Juan García-de-Lomas,1* and the Spanish Pneumococcal Infection Study Network{dagger}

Department of Microbiology, University Clinical Hospital,1 Unit of Pneumology, Department of Pediatrics, University Clinical Hospital, Valencia, Spain2

Received 11 March 2004/ Returned for modification 3 May 2004/ Accepted 18 July 2004

The performance of the Binax NOW immunochromatographic test for detecting Streptococcus pneumoniae antigen in urine specimens from 103 children presenting underlying pulmonary diseases with no recent pneumococcal infection was assessed. Our data indicate that this assay is unlikely to be useful for discriminating between children with and without pneumococcal pneumonia.

* Corresponding author. Mailing address: Department of Microbiology, University Clinical Hospital, Av. Blasco Ibáñez 17, 46010 Valencia, Spain. Phone: 34-96 393 1317. Fax: 34-96 398 7836. E-mail: jglomas{at}retemail.es.

{dagger} Contributing participants in the Spanish Pneumococcal Infection Study Network are listed in Acknowledgments.

Journal of Clinical Microbiology, October 2004, p. 4853-4855, Vol. 42, No. 10
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.10.4853-4855.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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