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Journal of Clinical Microbiology, November 2004, p. 5394-5396, Vol. 42, No. 11
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.11.5394-5396.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Association between a High BK Virus Load in Urine Samples of Patients with Graft-Versus-Host Disease and Development of Hemorrhagic Cystitis after Hematopoietic Stem Cell Transplantation

G. Bogdanovic,1,2 P. Priftakis,1,{dagger} G. Giraud,1,{dagger} M. Kuzniar,1 R. Ferraldeschi,1 P. Kokhaei,1 H. Mellstedt,1 M. Remberger,3 P. Ljungman,4 J. Winiarski,5 and T. Dalianis1*

Department of Oncology-Pathology, Karolinska Institutet,1 Department of Clinical Microbiology, Karolinska Hospital,2 Centre of Allogenic Stem Cell Transplantation,3 Departments of Haematology,4 Paediatrics, Huddinge University Hospital, Stockholm, Sweden5

Received 14 March 2004/ Returned for modification 27 May 2004/ Accepted 22 June 2004

BK virus (BKV) load in urine alone or in combination with acute graft-versus-host disease (GVHD) was correlated to development of hemorrhagic cystitis (HC). BKV load in combination with acute GVHD discriminated the best, while BKV and viral load alone, but not GVHD, still showed predictive ability for HC.

* Corresponding author. Mailing address: Department of Oncology-Pathology, CCK, R8:01, Karolinska University Hospital, 171 76 Stockholm, Sweden. Phone: 46-8-51772593. Fax: 46-8-309195. E-mail: Tina.Dalianis{at}cck.ki.se.

{dagger} P.P. and G.G. contributed equally to this study.

Journal of Clinical Microbiology, November 2004, p. 5394-5396, Vol. 42, No. 11
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.11.5394-5396.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.





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