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Journal of Clinical Microbiology, November 2004, p. 5419-5423, Vol. 42, No. 11
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.11.5419-5423.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Fatal Cerebral Phaeohyphomycosis Due to Curvularia lunata in an Immunocompetent Patient

Elliot Carter* and Carole Boudreaux

Department of Pathology, University of South Alabama, Mobile, Alabama

Received 26 April 2004/ Returned for modification 4 June 2004/ Accepted 28 June 2004

Curvularia infections in humans are relatively uncommon despite the ubiquitous presence of this soil-dwelling dematiaceous fungus in the environment. Originally thought to be solely a pathogen of plants, Curvularia has been described as a pathogen of humans and animals in the last half-century, causing respiratory tract, cutaneous, and corneal infections. Only three previous cases of central nervous system involvement by Curvularia have been documented in the medical literature. We report a fatal case of cerebral Curvularia infection in which there was no known history of immunocompromise or prior respiratory tract or sinus infection in the patient.

* Corresponding author. Department of Pathology, University of South Alabama, 2451 Fillingim St., Mobile, AL 36617. Phone: (251) 471-7790. Fax: (251) 471-7884. E-mail: ecarter{at}usouthal.edu.

Journal of Clinical Microbiology, November 2004, p. 5419-5423, Vol. 42, No. 11
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.11.5419-5423.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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