This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Palmieri, F.
Right arrow Articles by Majori, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Palmieri, F.
Right arrow Articles by Majori, G.

 Previous Article  |  Next Article 

Journal of Clinical Microbiology, November 2004, p. 5424-5426, Vol. 42, No. 11
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.11.5424-5426.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

CASE REPORT

Genetic Confirmation of Quinine-Resistant Plasmodium falciparum Malaria Followed by Postmalaria Neurological Syndrome in a Traveler from Mozambique

Fabrizio Palmieri,1 Nicola Petrosillo,1* Maria Grazia Paglia,1 Aristide Conte,1 Delia Goletti,1 Leopoldo Paolo Pucillo,1 Michela Menegon,2 Anna Sannella,2 Carlo Severini,2 and Giancarlo Majori2

Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani, Istituto di Ricovero e Cura a Carattere Scientifico,1 Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità, Rome, Italy2

Received 29 April 2004/ Returned for modification 6 June 2004/ Accepted 9 July 2004

A case of quinine-resistant Plasmodium falciparum malaria, followed by a postmalaria neurological syndrome and a recurrence episode, is described. Genetic characterization of the P. falciparum isolate obtained by analysis of msp1 and msp2 amplicons revealed the coexistence of two genotypes causing the first malaria episode and the presence of a unique isolate responsible for the recurrence.

* Corresponding author. Mailing address: Istituto Nazionale per le Malattie Infettive "L. Spallanzani" IRCCS, II Divisione, Via Portuense 292, 00149 Rome, Italy. Phone: 39-0655170432. Fax: 39-0655170486. E-mail: petrosillo{at}inmi.it.

Journal of Clinical Microbiology, November 2004, p. 5424-5426, Vol. 42, No. 11
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.11.5424-5426.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Henry, M., Briolant, S., Zettor, A., Pelleau, S., Baragatti, M., Baret, E., Mosnier, J., Amalvict, R., Fusai, T., Rogier, C., Pradines, B. (2009). Plasmodium falciparum Na+/H+ Exchanger 1 Transporter Is Involved in Reduced Susceptibility to Quinine. Antimicrob. Agents Chemother. 53: 1926-1930 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»