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Journal of Clinical Microbiology, February 2004, p. 912-913, Vol. 42, No. 2
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.2.912-913.2004
Copyright © 2004, American Society of Microbiology. All Rights Reserved.

Immunologically Silent Autochthonous Acute Hepatitis E Virus Infection in France

Jean Michel Mansuy,1* Jean Marie Peron,2 Christophe Bureau,2 Laurent Alric,3 Jean Pierre Vinel,2 and Jacques Izopet1

Virology Laboratory,1 Department of Hepato-Gastro-Enterology,2 Department of Internal Medicine, Purpan University Hospital, 31059 Toulouse, France3

Received 5 August 2003/ Returned for modification 12 October 2003/ Accepted 4 November 2003

Hepatitis E is an acute and self-limiting hepatitis, and the causative agent, hepatitis E virus, is excreted in feces and orally transmitted. The disease is common in Asia and Africa, causing outbreaks or sporadic cases. In Europe, the infection is generally observed after a history of travel in an area of endemicity. We report on an autochthonous case in southwestern France in which the diagnosis was based on molecular tools rather than serological testing.

* Corresponding author. Mailing address: Virology Laboratory, Purpan University Hospital, 31059 Toulouse, France. Phone: 33 5 61 77 22 65. Fax: 33 5 61 77 25 42. E-mail: mansuy.jm{at}chu-toulouse.fr.

Journal of Clinical Microbiology, February 2004, p. 912-913, Vol. 42, No. 2
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.2.912-913.2004
Copyright © 2004, American Society of Microbiology. All Rights Reserved.



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