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Journal of Clinical Microbiology, March 2004, p. 1260-1262, Vol. 42, No. 3
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.3.1260-1262.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Susceptibility Pattern and Molecular Type of Species-Specific Candida in Oropharyngeal Lesions of Indian Human Immunodeficiency Virus-Positive Patients

Ali Abdul Lattif,1 Uma Banerjee,2 Rajendra Prasad,1 Ashutosh Biswas,3 Naveet Wig,3 Neeraj Sharma,4 Absarul Haque,4 Nivedita Gupta,4 Najma Z. Baquer,1 and Gauranga Mukhopadhyay4*

School of Life Sciences,1 Special Centre for Molecular Medicine, Jawaharlal Nehru University,4 Department of Microbiology,2 Department of Medicine, All India Institute of Medical Sciences, New Delhi, India3

Received 28 July 2003/ Returned for modification 29 August 2003/ Accepted 16 December 2003

A study of oropharyngeal candidiasis (OPC) in Indian human immunodeficiency virus (HIV)/AIDS patients was conducted over a period of 15 months. This study revealed that 75% of the HIV/AIDS patients had OPC. MIC testing revealed that 5% of the Candida isolates were fluconazole resistant. A correlation between CD4+-T-cell counts and development of OPC in HIV/AIDS patients was also observed. Molecular typing of C. albicans isolates showed that all were genetically unrelated.

* Corresponding author. Mailing address: Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi 110067, India. Phone: 91-11-26101044. Fax: 91-11-26186814. E-mail: garunga{at}hotmail.com.

Journal of Clinical Microbiology, March 2004, p. 1260-1262, Vol. 42, No. 3
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.3.1260-1262.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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