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Journal of Clinical Microbiology, March 2004, p. 1333-1336, Vol. 42, No. 3
0095-1137/04/$08.00+0 DOI: 10.1128/JCM.42.3.1333-1336.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.
A Canine Parvovirus Mutant Is Spreading in Italy
Vito Martella,1* Alessandra Cavalli,1 Annamaria Pratelli,1 Giancarlo Bozzo,1 Michele Camero,1 Domenico Buonavoglia,2 Donato Narcisi,1 Maria Tempesta,1 and Canio Buonavoglia1
Department of Animal Health and Wellbeing, University of Bari, Bari,1
Department of Pathology and Infectious Diseases, University of Messina, Messina, Italy2
Received 13 December 2002/
Returned for modification 26 May 2003/
Accepted 11 November 2003
By antigenic and genetic characterization of canine parvovirus type 2 (CPV-2) strains collected in 2001 and 2002 in Italy, it was possible to observe the spread of viruses with an unusual mutation, Glu-426, affecting a major antigenic epitope of CPV-2. Out of 67 strains analyzed, 49 (73.13%) were characterized as CPV-2a, 6 (8.95%) were characterized as CPV-2b, and 12 (17.91%) were characterized as the Glu-426 mutant.
* Corresponding author. Mailing address: Dipartimento di Sanità e Benessere Animale, Facoltà di Medicina Veterinaria di Bari, S.p. per Casamassima km 3, 70010, Valenzano, Bari, Italy. Phone: 39 080 4679833. Fax: 39 080 4679043. E-mail:
v.martella{at}veterinaria.uniba.it
Journal of Clinical Microbiology, March 2004, p. 1333-1336, Vol. 42, No. 3
0095-1137/04/$08.00+0 DOI: 10.1128/JCM.42.3.1333-1336.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.
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