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Journal of Clinical Microbiology, April 2004, p. 1770-1772, Vol. 42, No. 4
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.4.1770-1772.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Characterization of an Anonymous Molecular Marker Strongly Linked to Escherichia coli Strains Causing Neonatal Meningitis

Olivier Clermont, Stéphane Bonacorsi, and Edouard Bingen*

Laboratoire d'Études de Génétique Bactérienne dans les Infections de l'Enfant (EA3105), Université Denis Diderot-Paris 7, Service de Microbiologie, Hôpital Robert-Debré (AP-HP), Paris, France

Received 1 September 2003/ Returned for modification 16 October 2003/ Accepted 2 January 2004

An anonymous 14.9-kb rrn-containing HindIII fragment is strongly linked to Escherichia coli strains causing neonatal meningitis. We show in this report that this fragment does not encode new virulence factors but lacks arpA, a gene common in avirulent E. coli strains, and we developed a PCR test to detect this fragment.

* Corresponding author. Mailing address: Service de Microbiologie, Hôpital Robert Debré, 48 Blvd. Sérurier, 75395 Paris cedex 19, France. Phone: 33-1-40-03-23-40. Fax: 33-1-40-03-24-50. E-mail: edouard.bingen{at}rdb.ap-hop-paris.fr.

Journal of Clinical Microbiology, April 2004, p. 1770-1772, Vol. 42, No. 4
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.4.1770-1772.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.





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