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Journal of Clinical Microbiology, April 2004, p. 1779-1781, Vol. 42, No. 4
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.4.1779-1781.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Usefulness of Toxoplasma gondii-Specific Recombinant Antigens in Serodiagnosis of Human Toxoplasmosis

H. Pietkiewicz,1 E. Hiszczynska-Sawicka,2 J. Kur,2 E. Petersen,3,4 H. V. Nielsen,3 M. Stankiewicz,5 I. Andrzejewska,6 and P. Myjak1*

Department of Tropical Parasitology, Interfaculty Institute of Maritime and Tropical Medicine, Medical University of Gdansk, 81-519 Gdynia,1 Department of Microbiology, Gdansk University of Technology, 80-952 Gdansk,2 Department of Biology and Medical Parasitology, Medical University of Poznan, 87-100 Poznan, Poland,4 Laboratory of Parasitology, Statens Seruminstitut, DK-2300 Copenhagen, Denmark,3 Animal and Food Sciences Division, Lincoln University, Canterbury, New Zealand,5 Department of Laboratory Medicine, Karolinska Institute, S14186 Stockholm, Sweden6

Received 16 July 2003/ Returned for modification 10 November 2003/ Accepted 9 January 2004

Toxoplasma gondii SAG1, GRA1, and GRA7 recombinant antigens may be regarded as tools for the detection of T. gondii immunoglobulin G antibodies in persons with chronic and acute toxoplasmosis. GRA7 is more correlated with acute toxoplasmosis. A combination of these antigens will increase the sensitivity of enzyme-linked immunosorbent assays.

* Corresponding author. Mailing address: Department of Tropical Parasitology, Interfaculty Institute of Maritime and Tropical Medicine, Medical University of Gdansk, 81-519 Gdynia, ul. Powstania Styczniowego 9 b, Poland. Phone: 48-58-6998547. Fax: 48-58-6223354. E-mail: pemyjak{at}immt.gdynia.pl.

Journal of Clinical Microbiology, April 2004, p. 1779-1781, Vol. 42, No. 4
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.4.1779-1781.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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