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Journal of Clinical Microbiology, May 2004, p. 2227-2230, Vol. 42, No. 5
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.5.2227-2230.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Outbreak of Burkholderia cepacia Bacteremia in a Pediatric Hospital Due to Contamination of Lipid Emulsion Stoppers

C. Doit,1 C. Loukil,1 A.-M. Simon,1 A. Ferroni,2 J.-E. Fontan,3 S. Bonacorsi,1 P. Bidet,1 V. Jarlier,4 Y. Aujard,5 F. Beaufils,6 and E. Bingen1*

Service de Microbiologie,1 Service de Pharmacie,3 Service de Néonatologie,5 Service de Réanimation pédiatrique, Hôpital Robert Debré,6 Service de Microbiologie, Hôpital Necker-Enfants Malades,2 Département de l'information, de la recherche, de l'évaluation et de la qualité, Assistance Publique-Hôpitaux de Paris, Paris4

Received 14 October 2003/ Returned for modification 11 November 2003/ Accepted 12 January 2004

We describe a 7-month outbreak of nosocomial Burkholderia cepacia bacteremia involving eight children in a pediatric hospital and the results of epidemiological investigations. A B. cepacia strain genotypically identical to the blood isolates was recovered from the upper surface of capped rubber stoppers of bottles of a commercial lipid emulsion used for parenteral nutrition.


* Corresponding author. Mailing address: Service de Microbiology, Hôpital Robert Debré, 48 Bd Sérurier, 75019 Paris, France. Phone: 33 1 40 03 23 40. Fax: 33 1 40 03 24 50. E-mail: edouard.bingen{at}rdb.ap-hop-paris.fr.


Journal of Clinical Microbiology, May 2004, p. 2227-2230, Vol. 42, No. 5
0095-1137/04/$08.00+0     DOI: 10.1128/JCM.42.5.2227-2230.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.




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